Change jerks us out of this comfort zone by stimulating the prefrontal cortex, a section of the brain responsible for insight and impulse control. But the prefrontal cortex is also directly linked to the amygdala and that's the brain's fear circuitry, which in turn controls our freeze, fight or flight response. And when the prefrontal cortex is overwhelmed with complex and unfamiliar concepts, the amygdala connection gets knocked into high gear. The result is all those negative feelings of anxiety, fear, depression, sadness, fatigue or anger that change leaders observe in their teams (and often in themselves).
But if science helps explain our negative reaction to change, it also offers insights for helping people deal with change.